HRID885327

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID853161

4-Methyl-5-phenyl-1,3-oxazolidin-2-one

C10H11NO2

结构：CCOC(=O)Cc1ccc(OC)c(Oc2ccc(C(F)(F)F)cc2CBr)c1

HCID58237660

未命名化合物

PRODUCTS

生成物

结构：CCOC(=O)Cc1ccc(OC)c(Oc2ccc(C(F)(F)F)cc2CN2C(=O)O[C@H](c3ccccc3)[C@@H]2C)c1

HCID58237495

未命名化合物

PROCEDURE

实验过程

Prepared according to the procedure described in Example 11, Step 7, using the following starting materials: [3-(2-bromomethyl-4-trifluoromethyl-phenoxy)-4-methoxy-phenyl]-acetic acid ethyl ester and (4S,5R)-(−)-4-methyl-5-phenyl-2-oxazolidinone.

WORKUP

后处理

customPrepared

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-8e5da203e9674402a17c657cd7145512
来源数据集: uspto-grants-2012_08
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08242145B2
来源说明: uspto-grants-2012_08

反应 SMILES

[CH2:1]([O:3][C:4](=[O:27])[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([O:12][CH3:13])=[C:8]([O:14][C:15]2[CH:20]=[CH:19][C:18]([C:21]([F:24])([F:23])[F:22])=[CH:17][C:16]=2[CH2:25]Br)[CH:7]=1)[CH3:2].[CH3:28][C@H:29]1[C@@H:33]([C:34]2[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=2)[O:32][C:31](=[O:40])[NH:30]1>>[CH2:1]([O:3][C:4](=[O:27])[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([O:12][CH3:13])=[C:8]([O:14][C:15]2[CH:20]=[CH:19][C:18]([C:21]([F:24])([F:23])[F:22])=[CH:17][C:16]=2[CH2:25][N:30]2[C@@H:29]([CH3:28])[C@@H:33]([C:34]3[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=3)[O:32][C:31]2=[O:40])[CH:7]=1)[CH3:2]