HuagongsheHuagongshe Chemistry Print Report · For research reference only
(1S)-2-amino-1-phenylethan-1-ol → (3-{4-Bromo-2-[((S)-2-hydroxy-2-phenyl-ethylamino)-methyl]-phenoxy}-phenyl)-acetic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (1S)-2-amino-1-phenylethan-1-ol | HCID 643217 | — |
| Reactant | [3-(4-Bromo-2-formyl-phenoxy)-phenyl]-acetic acid methyl ester | HCID 58237467 | — |
| Product | (3-{4-Bromo-2-[((S)-2-hydroxy-2-phenyl-ethylamino)-methyl]-phenoxy}-phenyl)-acetic acid methyl ester | HCID 58237603 | — |
Reaction Steps
Prepared according to the procedure described in Example 45, Step 3, using the following starting materials: [3-(4-bromo-2-formyl-phenoxy)-phenyl]-acetic acid methyl ester and (S)-(+)-2-amino-1-phenylethanol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08242145B2 |
| Source dataset | uspto-grants-2012_08 |
| ORD ID | ord-8a7a0ea4a1964e90af28b3a18c071208 |
| Source note | uspto-grants-2012_08 |