[3-(4-Bromo-2-bromomethyl-phenoxy)-phenyl]acetic acid methyl ester → HCID 67105570, compound

HRID 885338Notes

Reaction equation

HRID 885338 reaction equation
[CH3:1][O:2][C:3](=[O:21])[CH2:4][C:5]1[CH:10]=[CH:9][CH:8]=[C:7]([O:11][C:12]2[CH:17]=[CH:16][C:15]([Br:18])=[CH:14][C:13]=2[CH2:19]Br)[CH:6]=1.[Cl:22][C:23]1[CH:36]=[CH:35][C:26]([O:27][C@H:28]2[O:32][C:31](=[O:33])[NH:30][C@@H:29]2[CH3:34])=[CH:25][CH:24]=1>>[CH3:1][O:2][C:3](=[O:21])[CH2:4][C:5]1[CH:10]=[CH:9][CH:8]=[C:7]([O:11][C:12]2[CH:17]=[CH:16][C:15]([Br:18])=[CH:14][C:13]=2[CH2:19][N:30]2[C@H:29]([CH3:34])[C@@H:28]([O:27][C:26]3[CH:35]=[CH:36][C:23]([Cl:22])=[CH:24][CH:25]=3)[O:32][C:31]2=[O:33])[CH:6]=1

Participants

3

Reactant 2

HCID 58237479[3-(4-Bromo-2-bromomethyl-phenoxy)-phenyl]acetic acid methyl esterHCID 67105573HCID 67105573, compound

Product 1

HCID 67105570HCID 67105570, compound

Procedure

Prepared according to the procedure described in Example 6, Step 5, using the following starting materials: [3-(4-bromo-2-bromomethyl-phenoxy)-phenyl]-acetic acid methyl ester and (4R,5S)-5-(4-chloro-phenoxy)-4-methyl-oxazolidin-2-one.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-0c954a98045345a98b1e2632451eaaf6
Source dataset
uspto-grants-2012_08
Patent number
US08242145B2

Reaction notes

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