[3-(4-Bromo-2-bromomethyl-phenoxy)-phenyl]acetic acid methyl ester → HCID 67105695, compound

HRID 885339Notes

Reaction equation

HRID 885339 reaction equation
[CH3:1][O:2][C:3](=[O:21])[CH2:4][C:5]1[CH:10]=[CH:9][CH:8]=[C:7]([O:11][C:12]2[CH:17]=[CH:16][C:15]([Br:18])=[CH:14][C:13]=2[CH2:19]Br)[CH:6]=1.[F:22][C:23]1[CH:24]=[C:25]([CH:34]=[C:35]([F:37])[CH:36]=1)[O:26][C@H:27]1[O:31][C:30](=[O:32])[NH:29][C@@H:28]1[CH3:33]>>[CH3:1][O:2][C:3](=[O:21])[CH2:4][C:5]1[CH:10]=[CH:9][CH:8]=[C:7]([O:11][C:12]2[CH:17]=[CH:16][C:15]([Br:18])=[CH:14][C:13]=2[CH2:19][N:29]2[C@H:28]([CH3:33])[C@@H:27]([O:26][C:25]3[CH:24]=[C:23]([F:22])[CH:36]=[C:35]([F:37])[CH:34]=3)[O:31][C:30]2=[O:32])[CH:6]=1

Participants

3

Reactant 2

HCID 58237479[3-(4-Bromo-2-bromomethyl-phenoxy)-phenyl]acetic acid methyl esterHCID 67105668HCID 67105668, compound

Product 1

HCID 67105695HCID 67105695, compound

Procedure

Prepared according to the procedure described in Example 6, Step 5, using the following starting materials: [3-(4-bromo-2-bromomethyl-phenoxy)-phenyl]-acetic acid methyl ester and (4R,5S)-5-(3,5-difluoro-phenoxy)-4-methyl-oxazolidin-2-one.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-3f1680d0b98f4042b9b8018d88fe4c24
Source dataset
uspto-grants-2012_08
Patent number
US08242145B2

Reaction notes

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