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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 885341Generated: October 26, 2026

(4R,5S)-(+)-4-Methyl-5-phenyl-2-oxazolidinone → {5-[4-Bromo-2-((4R,5S)-4-methyl-2-oxo-5-phenyl-oxazolidin-3-ylmethyl)-phenoxy]-2-trifluoromethyl-phenyl}-acetic acid ethyl ester

https://huagongshe.com/reaction/885341

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(4R,5S)-(+)-4-Methyl-5-phenyl-2-oxazolidinoneHCID 2733812—
Reactant[5-(4-Bromo-2-bromomethyl-phenoxy)-2-trifluoromethyl-phenyl]-acetic acid ethyl esterHCID 67105528—
Product{5-[4-Bromo-2-((4R,5S)-4-methyl-2-oxo-5-phenyl-oxazolidin-3-ylmethyl)-phenoxy]-2-trifluoromethyl-phenyl}-acetic acid ethyl esterHCID 67105658—

Reaction Steps

Prepared according to the procedure described in Example 24, Step 7, using the following starting materials: [5-(4-bromo-2-bromomethyl-phenoxy)-2-trifluoromethyl-phenyl]-acetic acid ethyl ester and (4R,5S)-4-methyl-5-phenyl-2-oxazolidinone.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08242145B2
Source datasetuspto-grants-2012_08
ORD IDord-239cc66aedb749b381c0167f85053b0a
Source noteuspto-grants-2012_08