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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 885346Generated: October 30, 2026

(4R,5S)-(+)-4-Methyl-5-phenyl-2-oxazolidinone → {3-[4-Chloro-2-((4R,5S)-4-methyl-2-oxo-5-phenyl-oxazolidin-3-ylmethyl)-phenoxy]-4-methoxy-phenyl}-acetic acid ethyl ester

https://huagongshe.com/reaction/885346

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(4R,5S)-(+)-4-Methyl-5-phenyl-2-oxazolidinoneHCID 2733812—
Reactant[3-(2-Bromomethyl-4-chloro-phenoxy)-4-methoxy-phenyl]-acetic acid ethyl esterHCID 58237456—
Product{3-[4-Chloro-2-((4R,5S)-4-methyl-2-oxo-5-phenyl-oxazolidin-3-ylmethyl)-phenoxy]-4-methoxy-phenyl}-acetic acid ethyl esterHCID 67105912—

Reaction Steps

Prepared according to the procedure described in Example 24, Step 7, using the following starting materials: [3-(2-bromomethyl-4-chloro-phenoxy)-4-methoxy-phenyl]-acetic acid ethyl ester and (4R,5S)-4-methyl-5-phenyl-2-oxazolidinone.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08242145B2
Source datasetuspto-grants-2012_08
ORD IDord-f1b5c11d651a4fc89718888cced1cf50
Source noteuspto-grants-2012_08