HCID 58237530, compound → {3-[4-Bromo-2-((4R,5S)-4-methyl-2-oxo-5-phenyl-oxazolidin-3-ylmethyl)-phenoxy]-4-methoxy-phenyl}-acetic acid methyl ester

HRID 885347Notes

Reaction equation

HRID 885347 reaction equation
[CH3:1][O:2][C:3](=[O:23])[CH2:4][C:5]1[CH:10]=[CH:9][C:8]([O:11][CH3:12])=[C:7]([O:13][C:14]2[CH:19]=[CH:18][C:17]([Br:20])=[CH:16][C:15]=2[CH2:21]Br)[CH:6]=1.Cl[C:25]1[CH:30]=[CH:29][C:28]([C@@H:31]2[O:35][C:34](=[O:36])[NH:33][C@@H:32]2[CH3:37])=[CH:27][CH:26]=1>>[CH3:1][O:2][C:3](=[O:23])[CH2:4][C:5]1[CH:10]=[CH:9][C:8]([O:11][CH3:12])=[C:7]([O:13][C:14]2[CH:19]=[CH:18][C:17]([Br:20])=[CH:16][C:15]=2[CH2:21][N:33]2[C@H:32]([CH3:37])[C@H:31]([C:28]3[CH:29]=[CH:30][CH:25]=[CH:26][CH:27]=3)[O:35][C:34]2=[O:36])[CH:6]=1

Participants

3

Reactant 2

HCID 58237530HCID 58237530, compoundHCID 58237646[3-(4-Bromo-2-bromomethyl-phenoxy)-4-methoxy-phenyl]-acetic acid methyl ester

Product 1

HCID 58237448{3-[4-Bromo-2-((4R,5S)-4-methyl-2-oxo-5-phenyl-oxazolidin-3-ylmethyl)-phenoxy]-4-methoxy-phenyl}-acetic acid methyl ester

Procedure

Prepared according to the procedure described in Example 6, Step 5, using the following starting materials: [3-(4-bromo-2-bromomethyl-phenoxy)-4-methoxy-phenyl]-acetic acid methyl ester and (4R,5S)-5-(4-chloro-phenyl)-4-methyl-oxazolidin-2-one.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-96b1608d6f9c40e58a5a3c9465dec879
Source dataset
uspto-grants-2012_08
Patent number
US08242145B2

Reaction notes

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