HCID 58237530, compound → HCID 58237497, compound

HRID 885348Notes

Reaction equation

HRID 885348 reaction equation
[CH2:1]([O:3][C:4](=[O:27])[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([O:12][CH3:13])=[C:8]([O:14][C:15]2[CH:20]=[CH:19][C:18]([C:21]([F:24])([F:23])[F:22])=[CH:17][C:16]=2[CH2:25]Br)[CH:7]=1)[CH3:2].Cl[C:29]1[CH:34]=[CH:33][C:32]([C@@H:35]2[O:39][C:38](=[O:40])[NH:37][C@@H:36]2[CH3:41])=[CH:31][CH:30]=1>>[CH2:1]([O:3][C:4](=[O:27])[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([O:12][CH3:13])=[C:8]([O:14][C:15]2[CH:20]=[CH:19][C:18]([C:21]([F:24])([F:23])[F:22])=[CH:17][C:16]=2[CH2:25][N:37]2[C@H:36]([CH3:41])[C@H:35]([C:32]3[CH:33]=[CH:34][CH:29]=[CH:30][CH:31]=3)[O:39][C:38]2=[O:40])[CH:7]=1)[CH3:2]

Participants

3

Reactant 2

HCID 58237530HCID 58237530, compoundHCID 58237660[3-(2-Bromomethyl-4-trifluoromethyl-phenoxy)-4-methoxy-phenyl]-acetic acid ethyl ester

Product 1

HCID 58237497HCID 58237497, compound

Procedure

Prepared according to the procedure described in Example 10, Step 7, using the following starting materials: [3-(2-Bromomethyl-4-trifluoromethyl-phenoxy)-4-methoxy-phenyl]-acetic acid ethyl ester and (4R,5S)-5-(4-chloro-phenyl)-4-methyl-oxazolidin-2-one.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-be35308f43994b40897d9bf634417bf2
Source dataset
uspto-grants-2012_08
Patent number
US08242145B2

Reaction notes

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