HRID885348

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID58237530

未命名化合物

结构：CCOC(=O)Cc1ccc(OC)c(Oc2ccc(C(F)(F)F)cc2CBr)c1

HCID58237660

未命名化合物

PRODUCTS

生成物

结构：CCOC(=O)Cc1ccc(OC)c(Oc2ccc(C(F)(F)F)cc2CN2C(=O)O[C@@H](c3ccccc3)[C@H]2C)c1

HCID58237497

未命名化合物

PROCEDURE

实验过程

Prepared according to the procedure described in Example 10, Step 7, using the following starting materials: [3-(2-Bromomethyl-4-trifluoromethyl-phenoxy)-4-methoxy-phenyl]-acetic acid ethyl ester and (4R,5S)-5-(4-chloro-phenyl)-4-methyl-oxazolidin-2-one.

WORKUP

后处理

customPrepared

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-be35308f43994b40897d9bf634417bf2
来源数据集: uspto-grants-2012_08
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08242145B2
来源说明: uspto-grants-2012_08

反应 SMILES

[CH2:1]([O:3][C:4](=[O:27])[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([O:12][CH3:13])=[C:8]([O:14][C:15]2[CH:20]=[CH:19][C:18]([C:21]([F:24])([F:23])[F:22])=[CH:17][C:16]=2[CH2:25]Br)[CH:7]=1)[CH3:2].Cl[C:29]1[CH:34]=[CH:33][C:32]([C@@H:35]2[O:39][C:38](=[O:40])[NH:37][C@@H:36]2[CH3:41])=[CH:31][CH:30]=1>>[CH2:1]([O:3][C:4](=[O:27])[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([O:12][CH3:13])=[C:8]([O:14][C:15]2[CH:20]=[CH:19][C:18]([C:21]([F:24])([F:23])[F:22])=[CH:17][C:16]=2[CH2:25][N:37]2[C@H:36]([CH3:41])[C@H:35]([C:32]3[CH:33]=[CH:34][CH:29]=[CH:30][CH:31]=3)[O:39][C:38]2=[O:40])[CH:7]=1)[CH3:2]