HuagongsheHuagongshe Chemistry Print Report · For research reference only
(4R,5S)-5-(3,5-difluoro-phenyl)-4-methyl-oxazolidin-2-one → (3-{4-Bromo-2-[(4R,5S)-5-(3,5-difluoro-phenyl)-4-methyl-2-oxo-oxazolidin-3-ylmethyl]-phenoxy}-4-methoxy-phenyl)-acetic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (4R,5S)-5-(3,5-difluoro-phenyl)-4-methyl-oxazolidin-2-one | HCID 58237579 | — |
| Reactant | [3-(4-Bromo-2-bromomethyl-phenoxy)-4-methoxy-phenyl]-acetic acid methyl ester | HCID 58237646 | — |
| Product | (3-{4-Bromo-2-[(4R,5S)-5-(3,5-difluoro-phenyl)-4-methyl-2-oxo-oxazolidin-3-ylmethyl]-phenoxy}-4-methoxy-phenyl)-acetic acid methyl ester | HCID 58237659 | — |
Reaction Steps
Prepared according to the procedure described in Example 6, Step 5, using the following starting materials: [3-(4-bromo-2-bromomethyl-phenoxy)-4-methoxy-phenyl]-acetic acid methyl ester and (4R,5S)-5-(3,5-difluoro-phenyl)-4-methyl-oxazolidin-2-one.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08242145B2 |
| Source dataset | uspto-grants-2012_08 |
| ORD ID | ord-4c32689f77e541608d6cbf3df46376db |
| Source note | uspto-grants-2012_08 |