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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 885356Generated: October 30, 2026

2-Bromo-1-methyl-1H-imidazole → {3-[4-(1-Methyl-1H-imidazol-2-yl)-2-((4S,5R)-4-methyl-2-oxo-5-phenyl-oxazolidin-3-ylmethyl)-phenoxy]-phenyl}-acetic acid ethyl ester

https://huagongshe.com/reaction/885356

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Bromo-1-methyl-1H-imidazoleHCID 2773262—
Reactant{3-[2-((4S,5R)-4-Methyl-2-oxo-5-phenyl-oxazolidin-3-ylmethyl)-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenoxy]-phenyl}-acetic acid ethyl esterHCID 58237457—
Product{3-[4-(1-Methyl-1H-imidazol-2-yl)-2-((4S,5R)-4-methyl-2-oxo-5-phenyl-oxazolidin-3-ylmethyl)-phenoxy]-phenyl}-acetic acid ethyl esterHCID 58237645—

Reaction Steps

Prepared according to the procedure described in Example 19, Step 3, using the following starting materials: {3-[2-((4S,5R)-4-methyl-2-oxo-5-phenyl-oxazolidin-3-ylmethyl)-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenoxy]-phenyl}-acetic acid ethyl ester and 2-bromo-1-methyl-1H-imidazole.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08242145B2
Source datasetuspto-grants-2012_08
ORD IDord-c4ae35cecf084b4ba54865b5b3f0fbb4
Source noteuspto-grants-2012_08