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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 885359Generated: October 29, 2026

4-Bromo-3,5-dimethyl-1,2-oxazole → {3-[4-(3,5-Dimethyl-isoxazol-4-yl)-2-((4S,5R)-4-methyl-2-oxo-5-phenyl-oxazolidin-3-ylmethyl)-phenoxy]-phenyl}-acetic acid ethyl ester

https://huagongshe.com/reaction/885359

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Bromo-3,5-dimethyl-1,2-oxazoleHCID 318421—
Reactant{3-[2-((4S,5R)-4-Methyl-2-oxo-5-phenyl-oxazolidin-3-ylmethyl)-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenoxy]-phenyl}-acetic acid ethyl esterHCID 58237457—
Product{3-[4-(3,5-Dimethyl-isoxazol-4-yl)-2-((4S,5R)-4-methyl-2-oxo-5-phenyl-oxazolidin-3-ylmethyl)-phenoxy]-phenyl}-acetic acid ethyl esterHCID 58237601—

Reaction Steps

Prepared according to the procedure described in Example 19, Step 3, using the following starting materials: {3-[2-((4S,5R)-4-methyl-2-oxo-5-phenyl-oxazolidin-3-ylmethyl)-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenoxy]-phenyl}-acetic acid ethyl ester and 4-bromo-3,5-dimethylisoxazole.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08242145B2
Source datasetuspto-grants-2012_08
ORD IDord-ae6e64bf792043ec9672e120cbd16ec0
Source noteuspto-grants-2012_08