HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 885364Generated: October 31, 2026
Hydrochloric Acid → HCID 58237633, compound
https://huagongshe.com/reaction/885364
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Methanol | HCID 887 | — |
| Reactant | HCID 58237533 | HCID 58237533 | — |
| Product | HCID 58237633 | HCID 58237633 | — |
Reaction Steps
To {4-hydroxy-3-[2-((4R,5S)-4-methyl-2-oxo-5-phenyl-oxazolidin-3-ylmethyl)-4-trifluoromethyl-phenoxy]-phenyl}-acetic acid (1.5 g, 3.74 mmol) in MeOH was added hydrochloric acid (4N in 1,4-dioxane), and the reaction was stirred at 80° C. for 2 hours. The mixture was concentrated to dryness, and the residue was worked-up with EtOAc and saturated aqueous NaHCO3 to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08242145B2 |
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| Source dataset | uspto-grants-2012_08 |
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| ORD ID | ord-3587263b857b4d798ae5f7277cb71fab |
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| Source note | uspto-grants-2012_08 |
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