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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 885388Generated: October 30, 2026

2-Fluoro-5-(trifluoromethyl)benzoyl Chloride → {3-[4-(2-Fluoro-5-trifluoromethyl-benzoylamino)-2-(2-oxo-oxazolidin-3-ylmethyl)-phenoxy]-4-methoxy-phenyl}-acetic acid ethyl ester

https://huagongshe.com/reaction/885388

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Fluoro-5-(trifluoromethyl)benzoyl ChlorideHCID 2734880—
Reactant{3-[4-Amino-2-(2-oxo-oxazolidin-3-ylmethyl)-phenoxy]-4-methoxy-phenyl}-acetic acid ethyl esterHCID 58237507—
Product{3-[4-(2-Fluoro-5-trifluoromethyl-benzoylamino)-2-(2-oxo-oxazolidin-3-ylmethyl)-phenoxy]-4-methoxy-phenyl}-acetic acid ethyl esterHCID 67105919—

Reaction Steps

Prepared according to the procedure described in Example 91, Step 3, using the following starting materials: {3-[4-amino-2-(2-oxo-oxazolidin-3-ylmethyl)-phenoxy]-4-methoxy-phenyl}-acetic acid ethyl ester and 2-fluoro-5-(trifluoromethyl)benzoyl chloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08242145B2
Source datasetuspto-grants-2012_08
ORD IDord-36969152cb254a018afa966bccabf856
Source noteuspto-grants-2012_08