HuagongsheHuagongshe Chemistry Print Report · For research reference only
(1R,2S)-(+)-cis-1-Amino-2-indanol → (3-{4-Bromo-2-[((1R,2S)-2-hydroxy-indan-1-ylamino)-methyl]-phenoxy}-4-methoxy-phenyl)-acetic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (1R,2S)-(+)-cis-1-Amino-2-indanol | HCID 2725045 | — |
| Reactant | [3-(4-Bromo-2-formyl-phenoxy)-4-methoxy-phenyl]acetic acid ethyl ester | HCID 58237615 | — |
| Product | (3-{4-Bromo-2-[((1R,2S)-2-hydroxy-indan-1-ylamino)-methyl]-phenoxy}-4-methoxy-phenyl)-acetic acid ethyl ester | HCID 58237487 | — |
Reaction Steps
Prepared according to the procedure described in Example 45, Step 3, using the following starting materials: [3-(4-bromo-2-formyl-phenoxy)-4-methoxy-phenyl]-acetic acid ethyl ester and (1R,2S)-(+)-cis-1-amino-2-indanol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08242145B2 |
| Source dataset | uspto-grants-2012_08 |
| ORD ID | ord-3f4fdaa2cc6d4d369bddb40551e8b7b9 |
| Source note | uspto-grants-2012_08 |