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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 885414Generated: October 25, 2026

4-(4-Chlorophenyl)-2-pyrrolidinone → (3-{4-Bromo-2-[4-(4-chloro-phenyl)-2-oxo-pyrrolidin-1-ylmethyl]-phenoxy}-phenyl)-acetic acid ethyl ester

https://huagongshe.com/reaction/885414

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(4-Chlorophenyl)-2-pyrrolidinoneHCID 185490—
Reactant[3-(4-Bromo-2-bromomethyl-phenoxy)-phenyl]-acetic acid ethyl esterHCID 58237602—
Product(3-{4-Bromo-2-[4-(4-chloro-phenyl)-2-oxo-pyrrolidin-1-ylmethyl]-phenoxy}-phenyl)-acetic acid ethyl esterHCID 58237462—

Reaction Steps

Prepared according to the procedure described in Example 116, Step 1, using the following starting materials: [3-(4-bromo-2-bromomethyl-phenoxy)-phenyl]-acetic acid ethyl ester and 4-(4-chloro-phenyl)-pyrrolidin-2-one.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08242145B2
Source datasetuspto-grants-2012_08
ORD IDord-3d49c5b89f944648a786f2dde64e4728
Source noteuspto-grants-2012_08