1-Methylimidazolidin-2-one → {3-[4-Bromo-2-(3-methyl-2-oxo-imidazolidin-1-ylmethyl)-phenoxy]-4-methoxy-phenyl}-acetic acid ethyl ester

HRID 885416Notes

Reaction equation

HRID 885416 reaction equation
[CH2:1]([O:3][C:4](=[O:24])[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([O:12][CH3:13])=[C:8]([O:14][C:15]2[CH:20]=[CH:19][C:18]([Br:21])=[CH:17][C:16]=2[CH2:22]Br)[CH:7]=1)[CH3:2].[CH3:25][N:26]1[CH2:30][CH2:29][NH:28][C:27]1=[O:31]>>[CH2:1]([O:3][C:4](=[O:24])[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([O:12][CH3:13])=[C:8]([O:14][C:15]2[CH:20]=[CH:19][C:18]([Br:21])=[CH:17][C:16]=2[CH2:22][N:28]2[CH2:29][CH2:30][N:26]([CH3:25])[C:27]2=[O:31])[CH:7]=1)[CH3:2]

Participants

3

Reactant 2

HCID 5676001-Methylimidazolidin-2-oneHCID 58237498[3-(4-Bromo-2-bromomethyl-phenoxy)-4-methoxy-phenyl]acetic acid ethyl ester

Product 1

HCID 58237546{3-[4-Bromo-2-(3-methyl-2-oxo-imidazolidin-1-ylmethyl)-phenoxy]-4-methoxy-phenyl}-acetic acid ethyl ester

Procedure

Prepared according to the procedure described in Example 116, Step 1, using the following starting materials: [3-(4-bromo-2-bromomethyl-phenoxy)-4-methoxy-phenyl]-acetic acid ethyl ester and 1-methyl-2-imidazolidinone.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-abec97be2025405d8c22d3e8e3e4fe0a
Source dataset
uspto-grants-2012_08
Patent number
US08242145B2

Reaction notes

Loading…