2-(2-Ethoxy-5,7-dimethyl-3H-imidazo[4,5-b]pyridin-3-yl)methyl-10,11-dihydro-5H-dibenzo[b,f]azepine → HCID 178437439, compound

HRID 885433Notes

Reaction equation

HRID 885433 reaction equation
C(O[C:4]1[N:14](CC2C=CC3NC4C=CC=CC=4CCC=3C=2)[C:7]2=[N:8][C:9]([CH3:13])=[CH:10][C:11]([CH3:12])=[C:6]2[N:5]=1)C.[CH2:31](OC1NC2=NC(C)=CC(C)=C2N=1)[CH3:32]>>[CH2:31]([C:4]1[NH:14][C:7]2=[N:8][C:9]([CH3:13])=[CH:10][C:11]([CH3:12])=[C:6]2[N:5]=1)[CH3:32]

Participants

3

Reactant 2

HCID 690191522-(2-Ethoxy-5,7-dimethyl-3H-imidazo[4,5-b]pyridin-3-yl)methyl-10,11-dihydro-5H-dibenzo[b,f]azepineHCID 178467357HCID 178467357, compound

Product 1

HCID 178437439HCID 178437439, compound

Procedure

[step 1] 2-(2-Ethoxy-5,7-dimethyl-3H-imidazo[4,5-b]pyridin-3-yl)methyl-10,11-dihydro-5H-dibenzo[b,f]azepine (324 mg, 33%) was obtained in the same manner as in step 1 of Example 1, using 2-ethoxy-5,7-dimethyl-3H-imidazo[4,5-b]pyridine (478 mg, 2.50 mmol), obtained in Reference Example 2, instead of 2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridine.

Sources & evidence

ORD record
ord-1e7f4e60454c4ed999a243c4c555a067
Source dataset
uspto-grants-2012_08
Patent number
US08242151B2

Reaction notes

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