Hydrochloric Acid → HCID 67245149, compound

Participants

Reaction Steps

A solution of Intermediate 60 (3.42 g, 7.4 mmol), water (20 mL) and concentrated HCl (5.5 mL) was heated at 140° C. for 12 hours. The reaction was cooled. The crude was extracted with ethyl acetate (50 mL) and washed with saturated solution of sodium bicarbonate (2×20 mL), water (2×20 mL) and brine (1×20 mL), dried (Na2SO4) and concentrated. The titled compound was obtained (2.52 g, 76%) as oil.

Provenance & Evidence