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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 885553Generated: October 31, 2026

2,2-Difluoro-4-phenylbutan-1-ol → 2,2-Difluoro-2-(3-methoxyphenyl)ethan-1-ol

https://huagongshe.com/reaction/885553

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,2-Difluoro-4-phenylbutan-1-olHCID 18425775—
ReactantEthyl Difluoro-(3-methoxyphenyl)acetateHCID 39058305—
Product2,2-Difluoro-2-(3-methoxyphenyl)ethan-1-olHCID 67244718—

Reaction Steps

Obtained from Intermediate 67 (4.35 g, 19 mmol) by the procedure described in Intermediate 2. The title compound was obtained (3.19 g, 90%) as oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08242177B2
Source datasetuspto-grants-2012_08
ORD IDord-ff86116b55354dc48792f2ddb0053355
Source noteuspto-grants-2012_08