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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 885560Generated: November 1, 2026

1-(4-Phenylbutoxy)hept-6-en-3-ol → 1-(2,2-Difluoro-2-phenylethoxy)hept-6-en-3-ol

https://huagongshe.com/reaction/885560

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(4-Phenylbutoxy)hept-6-en-3-olHCID 67244432—
Reactant3-(2,2-Difluoro-2-phenylethoxy)propanalHCID 86658313—
Product1-(2,2-Difluoro-2-phenylethoxy)hept-6-en-3-olHCID 6724539853%

Reaction Steps

Obtained from Intermediate 82 (1.86 g, 8.7 mmol) by the procedure described in Intermediate 14. Purification by column chromatography with silica gel eluting with ethyl acetate/n-hexane (1:6) gave the title compound (1.24 g, 53%) as oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08242177B2
Source datasetuspto-grants-2012_08
ORD IDord-f715de7b19b54e01b7feab6f8bf201a3
Source noteuspto-grants-2012_08