Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 885561Generated: November 2, 2026

1-(2,2-Difluoro-2-phenylethoxy)hept-6-en-3-ol → 1-(2,2-Difluoro-2-phenylethoxy)hept-6-en-3-one

https://huagongshe.com/reaction/885561

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2,2-Difluoro-2-phenylethoxy)hept-6-en-3-olHCID 67245398—
Reactant3-(4-Phenylbutoxy)propionaldehydeHCID 86658307—
Product1-(2,2-Difluoro-2-phenylethoxy)hept-6-en-3-oneHCID 6724681243%

Reaction Steps

Obtained from Intermediate 83 (4.3 g, 15.8 mmol) by the procedure described in Intermediate 13. Purification by column chromatography with silica gel eluting with ethyl acetate/n-hexane (1:5) gave the title compound (1.82 g, 43%) as oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08242177B2
Source datasetuspto-grants-2012_08
ORD IDord-fd9644f7591b4e9db7bb65c85ae0acba
Source noteuspto-grants-2012_08