HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Bromo-2,5-dichloro-3-nitrobenzene → 3-Bromo-2,5-dichloroaniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Bromo-2,5-dichloro-3-nitrobenzene | HCID 18354554 | — |
| Reactant | 2-Chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenamine | HCID 58164432 | — |
| Product | 3-Bromo-2,5-dichloroaniline | HCID 18354530 | 24% |
Reaction Steps
This material was prepared according to the procedure used for SM-9, step 2 using 1-bromo-2,5-dichloro-3-nitrobenzene. Purification by flash chromatography (SiO2, 0-30% EtOAc in heptane) provided 3-bromo-2,5-dichloroaniline (24%): LCMS(m/z) 239.9 (MH+), tR=1.03 minutes; 1H NMR (400 MHz, CDCl3) δ 4.28 (br s, 2H) 6.71 (d, J=2.4 Hz, 1H) 7.02 (d, J=2.4 Hz, 1H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08242260B2 |
| Source dataset | uspto-grants-2012_08 |
| ORD ID | ord-11800b3b5a7a4d82ab1aac570246be57 |
| Source note | uspto-grants-2012_08 |