Sodium Hydroxide → HCID 58320695, compound

HRID 885785Notes

Reaction equation

HRID 885785 reaction equation
C([O:4][CH2:5][C:6]1[CH:10]=[C:9]([C:11]([Cl:14])([Cl:13])[Cl:12])[N:8]([C:15]2[C:20]([Cl:21])=[CH:19][CH:18]=[CH:17][N:16]=2)[N:7]=1)(=O)C.[OH-].[Na+]>C(O)C.O>[Cl:21][C:20]1[C:15]([N:8]2[C:9]([C:11]([Cl:12])([Cl:13])[Cl:14])=[CH:10][C:6]([CH2:5][OH:4])=[N:7]2)=[N:16][CH:17]=[CH:18][CH:19]=1

Participants

5

Reactant 2

HCID 14798Sodium HydroxideHCID 58320704HCID 58320704, compound

Product 1

HCID 58320695HCID 58320695, compound

Reagents, catalysts & solvents 2

HCID 702EthanolSolventHCID 962WaterSolvent2×

Procedure

36.9 g of [1-(3-chloropyridin-2-yl)-5-(trichloromethyl)-1H-pyrazol-3-yl]methyl acetate were dissolved in 100 ml of ethanol, and 20 g of NaOH (as a 40% solution in water) were added. After 1 h, the mixture was diluted with 300 ml of water, and the product was filtered off, washed with water and dried. This gave 30 g (95%) of the product as a white solid.

Workup

  1. filtrationthe product was filtered off
  2. washwashed with water
  3. customdried

Sources & evidence

ORD record
ord-6f8057b7d06f458482df5249cd65d7d4
Source dataset
uspto-grants-2012_08
Patent number
US08242313B2

Reaction notes

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