HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Bromomethyl)tetrahydro-2H-pyran → HCID 67185563, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Bromomethyl)tetrahydro-2H-pyran | HCID 141917 | — |
| Reactant | 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole | HCID 2774010 | — |
| Product | HCID 67185563 | HCID 67185563 | — |
Reaction Steps
The title compound was prepared from pyrazole-4-boronic acid pinacol ester and 2-(bromomethyl)tetrahydro-2H-pyran according to Method AC (stirred in a sealed vial at r.t. for 16 h, then heating to 80° C. for 4 h before addition of further 2-(bromomethyl)-tetrahydro-2H-pyran, and heating to 80° C. for a further 2 days) and was isolated as a brown gum (75%). LCMS (ES+) 293 (M+H)+, RT 3.41 minutes (Method 1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08242116B2 |
| Source dataset | uspto-grants-2012_08 |
| ORD ID | ord-efb0781afab6476c997290cb88605f18 |
| Source note | uspto-grants-2012_08 |