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HRID886247

反应详情

EQUATION

反应方程式

HRID 886247 的结构方程式

REACTANTS

反应物

2
结构：CC1(C)OB(c2cncc(F)c2)OC1(C)C
HCID16414268

3-Fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine

C11H15BFNO2

结构：CC(C)n1nc(N)nc1-c1cn2c(n1)-c1ccc(Br)cc1OCC2
HCID58204439

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)n1nc(N)nc1-c1cn2c(n1)-c1ccc(-c3cncc(F)c3)cc1OCC2
HCID58204880

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：[Pd]
催化剂HCID23938

Palladium

Pd

PROCEDURE

实验过程

5-(8-Bromo-4,5-dihydro-6-oxa-1,3a-diaza-benzo[e]azulen-2-yl)-1-isopropyl-1H-[1,2,4]triazol-3-ylamine was reacted with 3-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine were reacted under Suzuki palladium coupling conditions. The crude product was purified by reverse phase HPLC to give 241. LCMS: 406.2

WORKUP

后处理

  1. customThe crude product was purified by reverse phase HPLC