Bromoacetonitrile → {2-Methyl-4-[(2-methylpyridin-4-yl)ethynyl]-1H-imidazol-1-yl}acetonitrile

HRID 8867Notes

Reaction equation

[CH3:1][C:2]1[CH:7]=[C:6]([C:8]#[C:9][C:10]2[N:11]=[C:12]([CH3:15])[NH:13][CH:14]=2)[CH:5]=[CH:4][N:3]=1.Br[CH2:17][C:18]#[N:19]>>[CH3:15][C:12]1[N:13]([CH2:17][C:18]#[N:19])[CH:14]=[C:10]([C:9]#[C:8][C:6]2[CH:5]=[CH:4][N:3]=[C:2]([CH3:1])[CH:7]=2)[N:11]=1

Participants

Reactant 2

HCID 11534Bromoacetonitrile

HCID 178418884HCID 178418884, compound

Product 1

HCID 69292915{2-Methyl-4-[(2-methylpyridin-4-yl)ethynyl]-1H-imidazol-1-yl}acetonitrile

Procedure

The title compound, MS: m/e=237.2 (M+H+), was prepared in accordance with the general method of example 1 from 2-methyl-4-(2-methyl-1H-imidazol-4-ylethynyl)-pyridine and bromoacetonitrile.

Sources & evidence

ORD record: ord-968e7d53e00a490e98435e4b46f07c1f
Source dataset: uspto-grants-2006_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07091222B2

Reaction notes

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