Hydrogen chloride-ethyl acetate → HCID 68580287, compound

Participants

Reaction Steps

A solution of tert-butyl 8-(morpholin-4-yl)-2,3-dihydro-1,4-benzoxazepine-4(5H)-carboxylate (50.0 mg, 0.150 mmol) in 4N hydrogen chloride-ethyl acetate (1 ml) was stirred for 1 hr at room temperature, and the solvent was evaporated under reduced pressure. The residue was recrystallized from a mixed solvent of methanol and ether to give the desired product (25.0 mg, 54.5%) as a solid.

Provenance & Evidence