Hydrogen chloride-ethyl acetate → HCID 68578424, compound

Participants

Reaction Steps

A solution of tert-butyl 8-(piperidin-1-yl)-2,3-dihydro-1,4-benzoxazepine-4(5H)-carboxylate (280 mg, 0.843 mmol) in 4N hydrogen chloride-ethyl acetate (6 ml) was stirred for 1 hr at room temperature, and the solvent was evaporated under reduced pressure. The residue was recrystallized from a mixed solvent of methanol and ether to give the desired product (210 mg, 81.7%) as a solid.

Provenance & Evidence