Hydrogen chloride-ethyl acetate → HCID 68578642, compound

Participants

Reaction Steps

A mixture of tert-butyl 9-(2-methylphenyl)-2,3-dihydro-1,4-benzoxazepine-4(5H)-carboxylate (180 mg, 0.530 mmol), ethyl acetate (1 ml) and 4N hydrogen chloride-ethyl acetate solution (4 ml) were stirred for 1 hr at room temperature, and the solvent was evaporated under reduced pressure. The residue was recrystallized from a mixed solvent of methanol and ether to give the desired product (120 mg, 82.2%) as a solid.

Provenance & Evidence