Hydrogen chloride-ethyl acetate → HCID 68578412, compound

Participants

Reaction Steps

A mixture of tert-butyl 9-(3-thienyl)-2,3-dihydro-1,4-benzoxazepine-4(5H)-carboxylate (140 mg, 0.422 mmol), ethyl acetate (1 ml) and 4N hydrogen chloride-ethyl acetate solution (4 ml) was stirred for 1 hr at room temperature, and the solvent was evaporated under reduced pressure. The residue was recrystallized from a mixed solvent of methanol and ether to give the desired product (105 mg, 92.9%) as a solid.

Provenance & Evidence