Hydrogen chloride-ethyl acetate → HCID 68579408, compound

Participants

Reaction Steps

A mixture of tert-butyl 9-(1-methylethyl)-2,3-dihydro-1,4-benzoxazepine-4(5H)-carboxylate (330 mg, 1.13 mmol), ethyl acetate (6 ml) and 4N hydrogen chloride-ethyl acetate solution (3 ml) was stirred at room temperature for 1 hr, and the solvent was evaporated under reduced pressure. The residue was recrystallized from a mixed solvent of methanol and ether to give the desired product (106 mg, 97.2%) as a solid.

Provenance & Evidence