Hydrochloric Acid → HCID 57420173, compound

Participants

Reaction Steps

To a solution of the 2-oxo-1,2,3,4-tetrahydroquinolin-7-yl 4-(4-(methoxy-phenyl)piperazin-1-yl)butanoate (19a) (0.1 g) in 2 mL dichloromethane was added 4 mL 2M HCl solution in diethyl ether. The mixture was stirred at room temperature for 30 minutes. The solvent was evaporated, residue was triturated with ether, and solid precipitated was filtered, washed with ether and dried to give 2-oxo-1,2,3,4-tetrahydroquinolin-7-yl 4-(4-(2-methoxyphenyl)piperazin-1-yl)butanoate hydrochloride 20a. The hydrochloride salt 20a gave satisfactory 1H NMR spectral data. White solid, 0.106 g (98%). MS (ESI): m/z=424.1 (M+H+).

Provenance & Evidence