5-Bromo-8-nitroisoquinoline → Isoquinolin-8-amine
Reaction equation
Br[C:2]1[CH:11]=[CH:10][C:9]([N+:12]([O-])=O)=[C:8]2[C:3]=1[CH:4]=[CH:5][N:6]=[CH:7]2>[Pd]>[CH:7]1[C:8]2[C:3](=[CH:2][CH:11]=[CH:10][C:9]=2[NH2:12])[CH:4]=[CH:5][N:6]=1Participants
3
Reactant 1
Product 1
Reagents, catalysts & solvents 1
Procedure
The product from Example 57B was treated with Pd/C under a hydrogen atmosphere to provide the title compound.
Sources & evidence
- ORD record
- ord-f40615c2caac4b8e873de4068b9a87fe
- Source dataset
- uspto-grants-2012_08
- Patent number
- US08247413B2
Reaction notes
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