HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 887552Generated: October 30, 2026
Potassium Carbonate → 2,2-Dimethyl-6-nitro-2H-benzo[B][1,4]oxazin-3(4H)-one
https://huagongshe.com/reaction/887552
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2-Bromo-N-(2-hydroxy-5-nitro-phenyl)-2-methyl-propionamide | HCID 10566329 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2,2-Dimethyl-6-nitro-2H-benzo[B][1,4]oxazin-3(4H)-one | HCID 10656631 | — |
Reaction Steps
2-Bromo-N-(2-hydroxy-5-nitro-phenyl)-2-methyl-propionamide was mixed with K2CO3 in 20 mL of DMF and stirred overnight at 50° C. The reaction mixture was poured into ice H2O. The precipitate was collected by filtration and washed with H2O. The crude compound was recrystallized from EtOH.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08247430B2 |
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| Source dataset | uspto-grants-2012_08 |
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| ORD ID | ord-dfed75f3a6ff4cad8c274fda371e74e2 |
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| Source note | uspto-grants-2012_08 |
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