HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 2-(2,4-dinitrophenyl)acetate → 6-Amino-1,3-dihydro-2H-indol-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 2-(2,4-dinitrophenyl)acetate | HCID 286146 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 6-Amino-1,3-dihydro-2H-indol-2-one | HCID 590538 | — |
Reaction Steps
An EtOH solution of (2,4-dinitro-phenyl)-acetic acid methyl ester was treated with H2 balloon and catalyzed with Pd/c (10%, 500 mg) at RT. The resulting mixture was filtered through a layer of Celite® and concentrated in vacuum to afford the desired compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08247430B2 |
| Source dataset | uspto-grants-2012_08 |
| ORD ID | ord-3139dab6d7b34d719cb04065f1825039 |
| Source note | uspto-grants-2012_08 |