HCID 21961374, compound → 1-Ethyl-4,4-dimethyl-1,2,3,4-tetrahydroquinolin-7-amine

Participants

Reaction Steps

The mixture of 1-ethyl-4,4-dimethyl-7-nitro-1,2,3,4-tetrahydro-quinoline (0.28 g) and Pd/C (0.060 g, 10% wt) in 10 ml of EtOAc was placed under H2 which was provided by a balloon and stirred at RT overnight. Then the mixture was filtered through Celite®, condensed, and the residue was purified by flash column chromatography (2% of EtOAc in CH2Cl2). The titled compound was obtained as a pink oil. MS (ES+): 204.8 (M+H)+. Calc'd for C11H16N—204.31.

Provenance & Evidence