HCID 57855965, compound → HCID 57855894, compound

Participants

Reaction Steps

A solution of 5-methyl-6-nitro-2-trifluoromethyl-quinoline-7-carboxylic acid (1.40 g) in ethanol (100 mL) is hydrogenated at atmosphere pressure and ambient temperature in the presence of Raney-nickel catalyst. TLC analysis after 12 h shows reaction completion. The mixture is filtered over hyflo and the filtrate concentrated in vacuum. The residue is recrystallized from hexane/ethyl acetate to give 0.90 g of the title compound of the formula

Provenance & Evidence