HuagongsheHuagongshe Chemistry Print Report · For research reference only
Nitric Acid → 3-Acetylamino-6-bromo-2-nitro-benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Nitric Acid | HCID 944 | — |
| Reactant | 5-Acetamido-2-bromobenzoic acid | HCID 2734159 | — |
| Solvent | Water | HCID 962 | — |
| Product | 3-Acetylamino-6-bromo-2-nitro-benzoic acid | HCID 11403903 | 37% |
Reaction Steps
5-(Acetylamino)-2-bromobenzoic acid (5.00 g, 19.4 mmol) was gradually added to fuming nitric acid (10 mL) at 0° C., and the mixture was stirred at room temperature for 4 hr. Water was added to the reaction solution, and the precipitated crystals were collected by filtration to give the title compound (2.19 g, yield 37%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08247429B2 |
| Source dataset | uspto-grants-2012_08 |
| ORD ID | ord-b5474ff32d0c4ffd806e4e3938920c71 |
| Source note | uspto-grants-2012_08 |