反应详情

Ethyl 9-(cyanomethyl)-2-methyl-8,9-dihydro-7H-cyclopenta[c]pyrazolo[1,5-a]pyridine-1-carboxylate (145 mg, 0.512 mmol) and Raney cobalt (1.5 g) were suspended in 2M ammonia/methanol solution (50 mL), and the mixture was stirred under a hydrogen atmosphere at room temperature for 14 hr. The catalyst was filtered off through celite, and the filtrate was concentrated under reduced pressure to give the title compound (145 mg, yield 99%).

1. filtrationThe catalyst was filtered off through celite
2. concentrationthe filtrate was concentrated under reduced pressure