反应详情

Ethyl 9-(cyanomethyl)-2-ethyl-8,9-dihydro-7H-cyclopenta[c]pyrazolo[1,5-a]pyridine-1-carboxylate (80.0 mg, 0.269 mmol) and Raney cobalt (800 mg) were suspended in 2M ammonia/ethanol solution (13 mL), and the mixture was stirred under a hydrogen atmosphere at room temperature for 4 hr. The catalyst was filtered off through celite, and the filtrate was concentrated under reduced pressure to give the title compound (81.0 mg, yield 100%).

1. filtrationThe catalyst was filtered off through celite
2. concentrationthe filtrate was concentrated under reduced pressure