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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 8878Generated: October 25, 2026

Bromocyclobutane → 4-[(1-Cyclobutyl-2-methyl-1H-imidazol-4-yl)ethynyl]-2-methylpyridine

https://huagongshe.com/reaction/8878

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBromocyclobutaneHCID 78110—
ReactantHCID 178418884HCID 178418884—
Product4-[(1-Cyclobutyl-2-methyl-1H-imidazol-4-yl)ethynyl]-2-methylpyridineHCID 69292178—

Reaction Steps

The title compound, MS: m/e=252.4 (M+H+), was prepared in accordance with the general method of example 1 from 2-methyl-4-(2-methyl-1H-imidazol-4-ylethynyl)-pyridine and bromocyclobutane.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07091222B2
Source datasetuspto-grants-2006_08
ORD IDord-a0776d4ce5d849729060245e1cc1d258
Source noteuspto-grants-2006_08