HCID 68702943, compound → HCID 25025108, compound

Participants

Reaction Steps

To a solution of N-[2-(5-fluoro-2-methyl-6,7-dihydrocyclopenta[e]indazol-8(2H)-ylidene)ethyl]propanamide (83.2 mg, 0.290 mmol) in methanol (2.9 mL) was added palladium-carbon powder (8.3 mg), and the mixture was stirred under a hydrogen atmosphere at room temperature for 7 hr. The catalyst was filtered off, and the filtrate was concentrated under reduced pressure. The residue was purified by silica gel column chromatography (methanol/ethyl acetate=0/100→15/85) to give the title compound (77.2 mg, yield 92%).

Provenance & Evidence