Potassium Carbonate → HCID 24877032, compound

Participants

Reaction Conditions

Reaction Steps

General procedure for preparing compounds 42 and 43: A mixture of compound 6 (100 mg, 0.26 mmol), compound La or Lb (0.3 mmol) and K2CO3 (200 mg) in DMF (1 mL) was shaken at 40° C. for 16 hours. After cooling to room temperature, the reaction mixture was quenched with water, extracted with CHCl3, concentrated and purified by column (silica gel, EtOAc/hexanes 1/1) to give the desired product as a free base. The free base was converted to its HCl-salt by treating with HCl (1 N aqueous) and drying under vacuum.

Provenance & Evidence