HCID 86619729, compound → 2-{[(17-Amino-3,6,9,12,15-pentaoxaheptadecan-1-yl)carbamoyl]methoxy}acetic acid

HRID 887964Notes

Reaction equation

HRID 887964 reaction equation
[N:1]([CH2:4][CH2:5][O:6][CH2:7][CH2:8][O:9][CH2:10][CH2:11][O:12][CH2:13][CH2:14][O:15][CH2:16][CH2:17][O:18][CH2:19][CH2:20][NH:21][C:22](=[O:29])[CH2:23][O:24][CH2:25][C:26]([OH:28])=[O:27])=[N+]=[N-]>O>[NH2:1][CH2:4][CH2:5][O:6][CH2:7][CH2:8][O:9][CH2:10][CH2:11][O:12][CH2:13][CH2:14][O:15][CH2:16][CH2:17][O:18][CH2:19][CH2:20][NH:21][C:22](=[O:29])[CH2:23][O:24][CH2:25][C:26]([OH:28])=[O:27]

Participants

3

Reactant 1

HCID 86619729HCID 86619729, compound

Product 1

HCID 866197302-{[(17-Amino-3,6,9,12,15-pentaoxaheptadecan-1-yl)carbamoyl]methoxy}acetic acid

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

23-Azido-5-oxo-6-aza-3,9,12,15,18,21-hexaoxatricosanoic acid (9.0 g, 21 mmol) was dissolved in water (50 mL) and reduced using H2(g)-Pd/C (10%). The reaction was run until ESI-MS analysis showed complete conversion to the desired product (MH+ calculated: 397.2. found 397.6). The crude product was used in the next step without further purification.

Sources & evidence

ORD record
ord-b95b67b96b0f4ceb9670299e4b45e8b6
Source dataset
uspto-grants-2012_08
Patent number
US08247534B2

Reaction notes

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