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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 888087Generated: October 25, 2026

Piperidine, 1-methyl,4-methylene- → N-[3-(1-Methyl-piperidin-4-ylmethyl)-5-trifluoromethyl-phenyl]-acetamide

https://huagongshe.com/reaction/888087

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPiperidine, 1-methyl,4-methylene-HCID 139537—
ReactantN-[3-(3-Piperidin-1-yl-propyl)-5-trifluoromethyl-phenyl]-acetamideHCID 21959446—
ProductN-[3-(1-Methyl-piperidin-4-ylmethyl)-5-trifluoromethyl-phenyl]-acetamideHCID 69435668—

Reaction Steps

N-[3-(1-Methyl-piperidin-4-ylmethyl)-5-trifluoromethyl-phenyl]-acetamide was prepared from 1-Methyl-4-methylene-piperidine similar to that described in the preparation of N-[3-(3-piperidin-1-yl-propyl)-5-trifluoromethyl-phenyl]-acetamide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08247556B2
Source datasetuspto-grants-2012_08
ORD IDord-6cba07ca4b0b40b99888a42cfdde22bf
Source noteuspto-grants-2012_08