3-Methoxy-5-nitrobenzotrifluoride → 5-Nitro-2-(trifluoromethyl)phenol

HRID 888093Notes

Reaction equation

HRID 888093 reaction equation
COC1C=C(C(F)(F)[F:10])C=C([N+]([O-])=O)C=1.[N+:16]([C:19]1[CH:20]=[CH:21][C:22]([C:26]([F:32])([F:31])C(F)(F)F)=[C:23]([OH:25])[CH:24]=1)([O-:18])=[O:17]>>[N+:16]([C:19]1[CH:20]=[CH:21][C:22]([C:26]([F:31])([F:32])[F:10])=[C:23]([OH:25])[CH:24]=1)([O-:18])=[O:17]

Participants

3

Reactant 2

HCID 5205973-Methoxy-5-nitrobenzotrifluorideHCID 17756181Phenol, 5-nitro-2-(1,1,2,2,2-pentafluoroethyl)-

Product 1

HCID 219595865-Nitro-2-(trifluoromethyl)phenol

Procedure

5-Nitro-2-trifluoromethyl-phenol was prepared from 1-Methoxy-3-nitro-5-trifluoromethyl-benzene similar to that described in the preparation of 5-nitro-2-pentafluoroethylphenol.

Sources & evidence

ORD record
ord-0455669d283f4d1080b424c24d7268df
Source dataset
uspto-grants-2012_08
Patent number
US08247556B2

Reaction notes

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