反应详情

To a stirred suspension of 4-cyano-7-azaindole (1 g, 6.0 mmol) in t-BuOH (60 mL) was added pyridinium tribromide (6.5 g, 20.19 mmol) by small portions. The solution was stirred at RT for 2 h and water was added. Solvent was evaporated, a solid precipitated which was filtered, rinsed quickly with IPOH and dried to give 3,3-dibromo-2-oxo-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine-4-carbonitrile.

1. customSolvent was evaporated
2. customa solid precipitated which
3. filtrationwas filtered
4. washrinsed quickly with IPOH
5. customdried