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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 888137Generated: October 30, 2026

n-(4-Tert-butylphenyl)-2-fluoronicotinamide → N-(4-tert-Butylphenyl)-2-[(1H-pyrrolo[2,3-b]pyridin-6-ylmethyl)amino]nicotinamide

https://huagongshe.com/reaction/888137

Reaction equation

Participants

RoleNameHCIDCharge
Reactantn-(4-Tert-butylphenyl)-2-fluoronicotinamideHCID 21959540—
Reactant2225154-13-0HCID 69264738—
ProductN-(4-tert-Butylphenyl)-2-[(1H-pyrrolo[2,3-b]pyridin-6-ylmethyl)amino]nicotinamideHCID 16225622—

Reaction Steps

The titled compound was prepared from N-(4-tert-butyl-phenyl)-2-fluoro-nicotinamide and C-(1H-pyrrolo[2,3-b]pyridin-6-yl)-methylamine dihydrochloride by the method described in Step A of Example 1. MS (ES+): 400 (M+H). Calc'd. for C24H25N5O—399.50.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08247556B2
Source datasetuspto-grants-2012_08
ORD IDord-c1e9ef1c4f7d4b6082e9259a42115bf4
Source noteuspto-grants-2012_08