HuagongsheHuagongshe Chemistry Print Report · For research reference only
(1h-Pyrrolo[2,3-b]pyridin-4-yl)methanamine dihydrochloride → N-(1-Acetyl-3,3-dimethyl-2,3-dihydro-1H-indol-6-yl)-2-[(1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)amino]nicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (1h-Pyrrolo[2,3-b]pyridin-4-yl)methanamine dihydrochloride | HCID 69263704 | — |
| Reactant | N-(1-acetyl-3,3-dimethyl-2,3-dihydro-1H-indol-6-yl)-2-fluoro-nicotinamide | HCID 69437396 | — |
| Product | N-(1-Acetyl-3,3-dimethyl-2,3-dihydro-1H-indol-6-yl)-2-[(1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)amino]nicotinamide | HCID 16225624 | — |
Reaction Steps
The titled compound was prepared from N-(1-acetyl-3,3-dimethyl-2,3-dihydro-1H-indol-6-yl)-2-fluoro-nicotinamide and C-(1H-pyrrolo[2,3-b]pyridin-4-yl)-methylamine dihydrochloride by the method described in Step A of Example 1. MS (ES+): 455 (M+H). Calc'd. for C26H26N6O2—454.53.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08247556B2 |
| Source dataset | uspto-grants-2012_08 |
| ORD ID | ord-e82da61511314d0ea2bdea7729766f95 |
| Source note | uspto-grants-2012_08 |