HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-(tert-butoxycarbonyl)glycine → N-(1-Glycyl-3,3-dimethyl-2,3-dihydro-1H-indol-6-yl)-2-[(1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)amino]nicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-(tert-butoxycarbonyl)glycine | HCID 78288 | — |
| Reactant | HCID 16225004 | HCID 16225004 | — |
| Product | N-(1-Glycyl-3,3-dimethyl-2,3-dihydro-1H-indol-6-yl)-2-[(1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)amino]nicotinamide | HCID 16224422 | — |
Reaction Steps
The titled compound was prepared from N-(3,3-dimethyl-2,3-dihydro-1H-indol-6-yl)-2-[(1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)amino]nicotinamide (Example 16) and tert-butoxycarbonylamino-acetic acid by the method described in Example 13. MS (ES+): 470 (M+H). Calc'd. for C26H27N7O2—469.55.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08247556B2 |
| Source dataset | uspto-grants-2012_08 |
| ORD ID | ord-f8404a81f2b443e48fda7cd04f600fcd |
| Source note | uspto-grants-2012_08 |